Abstract. Sulfation of chitosan (CS) Bombyx mori has been carried out using chlorosulfonic acid (CSA) as a sulfonating reagent. Optimal conditions for the production of chitosan sulfate (CHS) with a certain degree of hydrogen substitution of the amino group and hydroxyl group by the sulfo group and molecular structure have been revealed. Using the 6-311 ++ G (d. P) basis set of the B3LYP density functional method, the structure optimization and energy calculation have been performed for the CS and CSA models, as well as for the obtained sulfated derivatives.Biomedical testing of Bombyx mori chitosan sulfate samples has been carried out and their hypolipidic and anticoagulant properties have been revealed.
Key words. Bombyx mori CHS, CSA, quantum chemistry, biomedical practice.
DOI: http://uzpolymerjournal.com/articles/article.php?id=230211
Citation: Rakhmanova V.N., Milusheva R.Yu., Nurgaliev I.N., Rashidova S.Sh., SULPHATION OF BOMBYX MORI CHITOSAN AND STUDY OF THE REACTIVITY OF FUNCTIONAL GROUPS BY THE QUANTUM-CHEMICAL METHODOLOGY. Uzbekistan Journal of Polymers, Vol. 2(2) 2023: pp.109-115. DOI: http://uzpolymerjournal.com/articles/article.php?id=230211
Announcement text goes here and the text goes here. We present an action from which the dynamics of homogeneous cosmologies can be derived. The action has no dependence on scale within the system and hence is more parsimonious in its description than the Einstein-Hilbert action.
Text text goes here and the text goes here. We present an action from which the dynamics of homogeneous cosmologies can be derived. The action has no dependence on scale within the system and hence is more parsimonious in its description than the Einstein-Hilbert action.