Open Access Received:   |   Accepted:   |   Published:

PHYSICOCHEMICAL PROPERTIES OF POLYMER IMPLANT-FILMS FROM CARBOXYMETHYLCELLULOSE AND SILVER NANOPARTICLES FOR THE HEALING BURN WOUNDS

Jalilov J. Z., Yunusov Kh. E., Sarymsakov A. A., Rashidova S. Sh.

Institute of Polymer Chemistry and Physics, Uzbekistan Academy of Sciences, 100128, Tashkent, str А. Qodiriy., 7 “^b”

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Abstract. In this manuscript, we studied obtaining implant films for the treatment of burn wounds from silver nanoparticles (AgNPs) stabilized by sodium-carboxymethylcellulose (Na-CMC) with a degree of substitution (DS) of 0.65-0.90 and a degree of polymerization (DP) of 200-600 synthesized using the photochemical method. The structural, physicochemical and burn wound healing properties as well as the antimicrobial activity of implant films containing Na-CMC and AgNPs were studied.
The shape and size of AgNPs in the structure of Na-CMC solutions were determined by using UV–spectroscopy and atomic force microscopy analysis. It was found that the increase in silver nitrate concentration in the solution of Na-CMC followed by photo irradiation leads to a change in AgNP size and shape. It was found that Na-CMC films containing AgNPs in the range of sizes from 35-100 nm enhanced the antimicrobial activities and burn wound healing properties for 14 days.

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Key words. silver nanoparticles, sodium carboxymethylcellulose, UV spectroscopy, photochemical reduction, solution, synthesis.


DOI: http://uzpolymerjournal.com/articles/article.php?id=230107

*Corresponding author: Jalilov J. Z., Institute of Polymer Chemistry and Physics, Uzbekistan Academy of Sciences, 100128, Tashkent, str А. Qodiriy., 7 “^b”

Citation: Jalilov J. Z., Yunusov Kh. E., Sarymsakov A. A., Rashidova S. Sh., PHYSICOCHEMICAL PROPERTIES OF POLYMER IMPLANT-FILMS FROM CARBOXYMETHYLCELLULOSE AND SILVER NANOPARTICLES FOR THE HEALING BURN WOUNDS. Uzbekistan Journal of Polymers, Vol. 2(1) 2023: pp.72-81. DOI: http://uzpolymerjournal.com/articles/article.php?id=230107

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