Open Access Received: 04 September 2025   |   Accepted: 14 October 2025   |   Published: 10 November 2025

PREPARATION, CHARACTERIZATION, AND HEMOSTATIC PROPERTIES OF TRICARBOXYCELLULOSE

Kholturayev B.J., Yunusov Kh.E., Sarymsakov A.A.

Institute of Polymer Chemistry and Physics Uzbekistan Academy of Sciences, 100128, Tashkent, Uzbekistan

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Abstract. In this study, tricarboxycellulose samples were synthesized through the sequential oxidation of cellulose, woven gauze, and medical cotton using NaClO, NaIO₄, and H₂O₂. The resulting materials were thoroughly characterized in terms of their physicochemical and sorption properties. The oxidation process led to a substantial increase in the carboxyl group content, reaching 53% in cellulose, 46% in woven gauze, and 42% in medical cotton. Infrared (IR) spectroscopy confirmed structural modifications in cellulose, indicating the formation of new functional carboxyl groups. The modified tricarboxycellulose samples exhibited markedly improved sorption capacities-up to 830% for cellulose, 670% for woven gauze, and 520% for medical cotton. Owing to their enhanced sorption performance, biodegradability, and hemostatic properties, tricarboxycellulose-based materials show strong potential for application in medical settings as effective hemostatic agents.

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Key words. Tricarboxycellulose, oxidized cellulose, carboxyl group content, biodegradable, hemostatic biomaterials


DOI: http://uzpolymerjournal.com/articles/article.php?id=250304

*Corresponding author: Kholturayev B.J., Institute of Polymer Chemistry and Physics Uzbekistan Academy of Sciences, 100128, Tashkent, Uzbekistan

Citation: Kholturayev B.J., Yunusov Kh.E., Sarymsakov A.A., PREPARATION, CHARACTERIZATION, AND HEMOSTATIC PROPERTIES OF TRICARBOXYCELLULOSE. Uzbekistan Journal of Polymers, Vol. 4(3) 2025: pp.37-53. DOI: http://uzpolymerjournal.com/articles/article.php?id=250304

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